Sequential Analysis: Design Methods and Applications
نویسندگان
چکیده
Sequential tests have been used commonly in clinical trials to compare treatments. For sequential analysis of right-censored survival data with covariate adjustment, several different methods have been studied based on either Cox proportional hazards model or accelerated failure time model. Here we propose a test process based on linear transformation models for staggered entry data. The proposed test process is motivated by Chen et al.’s (2002) estimating equations for linear transformation models. We show that the test process can be approximated by a mean 0 multidimensional Gaussian process. A consistent estimator of its covariance matrix function is provided. For given interim analysis time points, a repeated significant test is developed based on the boundaries procedure proposed by Slud and Wei (1982). Numerical studies show that the proposed test process performs well.
منابع مشابه
Automatic measurement of instantaneous changes in the walls of carotid artery with sequential ultrasound images
Introduction: This study presents a computerized analyzing method for detection of instantaneous changes of far and near walls of the common carotid artery in sequential ultrasound images by applying the maximum gradient algorithm. Maximum gradient was modified and some characteristics were added from the dynamic programming algorithm for our applications. Methods: The algorithm was evaluat...
متن کاملApplications of Fuzzy Program Graph in Symbolic Checking of Fuzzy Flip-Flops
All practical digital circuits are usually a mixture of combinational and sequential logic. Flip–flops are essential to sequential logic therefore fuzzy flip–flops are considered to be among the most essential topics of fuzzy digital circuit. The concept of fuzzy digital circuit is among the most interesting applications of fuzzy sets and logic due to the fact that if there has to be an ultimat...
متن کاملA TRUST-REGION SEQUENTIAL QUADRATIC PROGRAMMING WITH NEW SIMPLE FILTER AS AN EFFICIENT AND ROBUST FIRST-ORDER RELIABILITY METHOD
The real-world applications addressing the nonlinear functions of multiple variables could be implicitly assessed through structural reliability analysis. This study establishes an efficient algorithm for resolving highly nonlinear structural reliability problems. To this end, first a numerical nonlinear optimization algorithm with a new simple filter is defined to locate and estimate the most ...
متن کاملWeights in block iterative methods
In this paper we introduce a sequential block iterative method and its simultaneous version with op-timal combination of weights (instead of convex combination) for solving convex feasibility problems.When the intersection of the given family of convex sets is nonempty, it is shown that any sequencegenerated by the given algorithms converges to a feasible point. Additionally for linear feasibil...
متن کاملA Small Printed Quadrifilar Helical Antenna for BGAN/GPS Applications
This paper presents an element of a 2×2-element array antenna for Inmarsat BGAN/GPS applications. The element is an axial mode printed quadrifilar helical antenna that has been integrated with a compact feed network to provide sequential phase rotation for circular polarization (CP) radiation. The novel integrated lumped-element feed network is designed to provide a balanced RF power to the fou...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012